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The BIG Shift

The BIG Shift by Ani Biome is the largest ever citizen science trial to longitudinally explore longevity - through the gut.


To fuel these algorithms, comprehensive datasets are essential. The BIG Shift study is designed to collect extensive real-world data to create the world’s largest longitudinal interventional longevity dataset. The study aims to open-source its findings to the global scientific community, continuously refining AI models to deliver increasingly precise and personalized health interventions.


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The Gut-Immune-Brain (BIG) axis is a crucial network that shapes cognitive health, emotional resilience, and immune function.

By leveraging advanced deep learning models, Ani Biome aims to map and modulate this axis.



Background

GUT MICROBIOME AS THE LONGEVITY CATALYST

The Gut

The BIG Shift is part of a larger initiative - the Human Gut Project.

We analyse the data from extensive clinical and preclinical trials we are conducting to map the brain-immune-gut axis, and design personalised microbiome-oriented interventions.

Personalised Cotherapies

50% of patients are non-responders to treatments. The number rises to 70% and more in oncology.

Gut microbiome defines if and how a person will respond to a drug.

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Digital +
Longitudinal

By measuring the effect longitudinally, and providing personalised cotherapies, we can affect the response rate and improve clinical outcomes.

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the Vitalligence Platform

This is where our bioactives, AgeBiotics, are personalized and evolve with each participant.

This is where our digital gut model comes alive, driving forward a deeper understanding of the brain-immune-gut axis.

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